মঙ্গলবার, ১ মে, ২০১২

Children with juvenile arthritis have higher rates of bacterial infection

ScienceDaily (May 1, 2012) ? Children with juvenile idiopathic arthritis (JIA) have higher rates of hospitalized bacterial infection than children without JIA according to an observational study appearing in Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology (ACR). The findings show that the risk of infection among JIA patients was significantly increased with use of high-dose glucocorticoids (steroids). Methotrexate (MTX) and tumor necrosis factor alpha (TNF) inhibitors were not found to increase infection risk in this pediatric population.

Arthritis is an inflammation of the joints that causes pain, swelling, stiffness and can lead to disability. JIA refers to chronic arthritis diseases that attack young patients and the ACR estimates close to 300,000 children in the U.S are affected. While immunosuppressant therapies such as steroids, MTX, and TNF inhibitors are used to treat JIA, it is unclear how they impact infection risk.

To compare bacterial infection incidence in children with and without JIA, a research team led by Dr. Timothy Beukelman from the University of Alabama at Birmingham used U.S. Medicaid data from 2000 to 2005. The team identified 8,479 JIA patients with 13,003 person-years of follow-up and a group of 360,489 children with attention-deficit hyperactivity disorder (ADHD) for comparison. Pharmacy claims were used to determine exposure to MTX, TNF inhibitors, and oral steroid medications. Infections were identified using hospital discharge diagnoses.

Researchers determined that 42% of JIA patients used MTX and 17% used TNF inhibitors to manage their disease. JIA patients without current exposure to MTX or TNF inhibitors had an increased rate of bacterial infection compared to patients with ADHD, even after adjusting for steroid use. "Patients with JIA who were not currently treated with MTX or TNF inhibitors had a 2-fold increase in hospitalized bacterial infection rates compared to children without arthritis," explains Dr. Beukelman, "This finding suggests the inflammatory or autoimmune process may predispose children to infection regardless of therapy."

Among children with JIA, the rate of infection associated with MTX or TNF inhibitor use was similar. After adjusting for MTX and TNF inhibitor use among children with JIA, high-dose steroid use -- 10 mg or more of prednisone daily -- more than doubled the rate of subsequent infection compared to patients not taking steroids. Dr. Beukelman concludes, "A steroid-sparing treatment strategy may reduce the risk of serious infection in children with JIA."

This research was supported by grants from the Agency for Healthcare Research and Quality (AHRQ), the Food and Drug Administration (FDA) U.S. Department of Health and Human Services (DHHS), and the National Institutes of Health (NIH).

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Story Source:

The above story is reprinted from materials provided by Wiley-Blackwell, via AlphaGalileo.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Timothy Beukelman, Fenglong Xie, Lang Chen, John W Baddley, Elizabeth Delzell, Carlos G Grijalva, James D Lewis, Rita Ouellet-Hellstrom, Nivedita M Patkar, Kenneth G Saag, Kevin L Winthrop and Jeffrey R Curtis on behalf of the Safety Assessment of Biological ThERapeutics (SABER) Collaboration. Rates of Hospitalized Bacterial Infection Associated with Juvenile Idiopathic Arthritis and Its Treatment. Arthritis & Rheumatism, 2012 DOI: 10.1002/art.34458)

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

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Hudson's sister to 911: 'Please help my mama'

By Gina Serpe and Claudia Rosenbaum, E! Online

David Banks / AP

Julia Hudson's 911 call was released Monday.

The dramatic and heartbreaking 911 call placed by Jennifer Hudson's sister upon finding the body of her mother has been released.

And it's exactly as gut-wrenchingly devastating and emotional as you would imagine.

More from E: Jennifer Hudson's sister testifies in family murder trial

The call was released this morning on the ruling of Judge Charles Burns, and against the plea by the prosecution not to do so.

"Help, please," Jennifer's sister Julia Hudson is heard telling the 911 operator. "Oh, God. Somebody's killed my mother, somebody's killed my mother...Please help me. Oh my God, oh my God."

When asked by the dispatcher if she needed an ambulance, a near-hysterical Hudson replied, "I don't know. I'm scared...please...please...can you please send an ambulance, please. Oh my God.

More from E: Jennifer Hudson, sister draw strength ahead of murder trial

"She's on the floor and I see blood coming from her head...I just came home from work and there's a bullet hole in our front door...she's 57 years old. Please help my mama. Please just send an ambulance," Julia says.

Toward the end of the three-minute call, while still on hold with the dispatcher, Julia can be heard speaking again, ostensibly to a neighbor.

"Where's my brother? What happened? She's on the floor...I'm here by myself."

More from E: Jennifer Hudson breaks down on stand

The call then cuts off. (Listen to the call on E! Online.)

The prosecution was opposed to the call being released, arguing on Friday that it had not yet been fully placed into evidence.

"To ensure the state's right to a fair trial and the defendant's right to a fair trial, we object at this time to releasing the 911 call," state attorney Jennifer Bagby argued Friday.

To no avail, as it turned out.

Photos from E:?Court appearances

Related content:

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How Content Marketers Can Reach a Larger Audience by ...

It is impossible for a week to pass without an important news story about eBooks. Of course these stories are about the ?other? eBooks ? the ones sold by Amazon and Barnes & Noble and read using Kindles, Nooks, tablets, and smartphones.

How do these ?commercial? eBooks differ from the PDF eBooks we marketers advocate? Three ways:

  1. PDF eBooks are not sold through Amazon and other online stores.
  2. PDF eBooks do not lend themselves to sharing on social networks.
  3. PDF eBooks provide a poor user experience on smartphones and tablets. They require too much pinching and panning to be easily read.

In fact, as screens get smaller?

  • Smartphone adoption reached 49.7 percent penetration in February 2012 and is expected to climb to 70 percent of all mobile phones by the end of 2013. (Nielsen)
  • The number of Americans owning at least one digital reading device (tablet, Kindle, Nook, etc.) jumped from 18 percent in December 2011 to 29 percent in January 2012 (Pew Internet)

? digital reading is going more mobile (according to Pew Internet?s 2012 study, The Rise of eReading):

  • 41 percent of readers of eBooks consume them on an eBook reader such as a Kindle or Nook.
  • 29 percent of readers of eBooks consume them on their cell phones.
  • 23 percent of readers of eBooks consume them on a tablet computer.

If the goal is to produce content that gets found, read, and shared, then content marketers can?t ignore mobile devices and online bookstores. Further, this adoption rate creates new opportunities for engagement and revenue generation.

Here?s a look at a few examples of the redefined, modern eBook.

The revenue opportunity

Making your eBook available in retail stores can expand your audience, and maybe even your bottom line.

Apple released its Lion operating system in July of 2011 and Ars Technica reviewer John Siracusa was ready with his detailed 27,000-word review. But instead of confining the article to the web, where it was available as an advertising-supported, 19-page, free document, Ars Technica formatted it for Kindle and sold it on Amazon for $4.99. Ars reported selling 3,000 copies in just the first 24 hours, which netted $10,500 ($4.99 x 3,000 x 70 percent royalty).

The marketing opportunity

Content marketers can convert their free PDF eBooks into regular eBooks to reach new readers.

The McKinsey Global Institute and the American Society of Golf Course Architects are examples of eBooks for marketing. Both create free content (as a PDF) to promote their organizations. These PDF eBooks are available for download from their website for free. But they take it a step further by formatting their content as eBooks and selling them on Amazon.

Making their information available in an online bookstore helps them reach an entirely new group of readers ? readers that may not have otherwise stumbled upon their website or information. This raises the question, ?Is Amazon becoming the Google for information products??

For these publishers, repurposing their content as paid eBooks is more about finding a new audience than it is about revenue generation. It also demonstrates that eBook buyers are willing to pay for the convenience and improved functionality of these eBooks.

Remember, you don?t have to charge

There are two major eBook file formats used by eReading devices. Amazon?s proprietary Mobi format and the ?industry standard? ePub format, used by virtually all other eBook retailers (including Apple, Sony and Barnes & Noble). Like PDF, both Mobi and ePub are free of distribution licensing fees.

If you plan to make your content available for free you can create a version in each file format ? Mobi, ePub and PDF ? and place them on your website to be available as downloads.

One great example of this implementation is the collection of free user guides published by MailChimp. Each of its 28 guides is available in all three formats in addition to being readable via a web browser.

Simply download the zip file and transfer the appropriate file to the eReading device of your choice. By including a PDF, your readers can also print the document (do people still do this!?).

Amazon?s Kindle eBooks can be shared via social networks

Has this happened to you: You?re reading a book and you come upon an interesting passage that you wish to share with your friends. With Kindle books (and perhaps others soon, too), you can share that passage on Facebook and/or Tweet it.

Ever wonder what other people highlight in their books? Visit a Kindle book page on Amazon and look for ?Popular Highlights.? You?ll see a list of favorite phrases and the number of people that highlighted them. What author wouldn?t love to find out what passages her readers found most interesting? (A great market research tool!)

The last social media benefit I?ll mention is Reading List by Amazon, a LinkedIn application that shares your reading list with other LinkedIn members. This is an opportunity for your readers to tell others that they are reading your book.

How to convert your content to Mobi and ePub formats

While not as painless as creating a PDF, this process is relatively straightforward for content marketers when you follow a few best practices. The good news is that new tools are coming out all the time, and there are third-party professionals skilled in producing eBooks.

But if you want to try to do it yourself, there are seven basic steps:

  1. Using Microsoft Word, follow best practices in formatting your document. Use style sheets, avoid extra lines, and don?t use spaces for tabs. Also, make sure graphics, charts, and tables are stored as jpeg or gif files. Insert these into the document where they belong. Keep in mind that text does not flow around images, so create your layout appropriately (text, then image, then text). There are no headers and footers in eBooks, so make sure to remove these in advance, so as not to create formatting issues.
  2. Most eBooks benefit from a linked table of contents to help the reader navigate the material. In Word, select Insert, then Bookmark to name the destination. Then link to it with Insert, Hyperlink. (Word?s table of contents auto-generator also works but could cause conversion problems later.)
  3. Download a copy of Calibre, a free (donations welcome) eBook library manager. This tool will help you convert your document to Mobi and ePub file formats.
  4. Save your Word document as a filtered HTML file. If your document includes images, you?ll need to combine the resultant HTML document (.htm) and image folder into a zip file before importing into Calibre.
  5. Invest in designing a professional-looking book cover. It is true what they say about judging books by the cover. It?s also important for branding.
  6. Download one of the free software eReaders from Amazon or B&N, or load your eBook on your eReader to see how it looks and check it for typos, layout problems, etc.
  7. If you plan to sell your eBook, you will want to set up a free account with Amazon?s Kindle Direct Publishing and/or Barnes & Noble?s Pubit.

(Note: You can click here for a free checklist of the steps necessary for publishing an eBook.)

Leverage your content investment by redefining the eBook

In today?s consumer-driven media landscape, the word eBook has a very different connotation. Creating mainstream or modern eBooks may not be relevant for every content project, but for the right ones, it can make a huge difference.

Want more content marketing inspiration? Download our ultimate eBook with 100 content marketing examples.

Cover image: Yutaka Tsutano

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Best affordable city hotels in the U.S.

Courtesy of Charleston Place Hotel

Charleston Place in Charleston, S.C., is home to 442 elegant rooms furnished with Chippendale-style furnishings and flat-screen TVs.

By Katrina Brown Hunt , Travel + Leisure

The Brown is a Kentucky institution: the Georgian Revival?style hotel in Louisville wows guests with marble flooring, ornate ceilings, feather beds ? and the Hot Brown, a decadent, open-faced turkey sandwich. Even more impressive, the rates start as low as $129.

Slideshow: See the hotels and where they're at

This irresistible combination of character and value makes The Brown one of America?s top affordable city hotels, as selected among high-scoring properties in Travel + Leisure's annual World?s Best reader survey. All these favorite hotels offer room rates between $90 and $250 a night ? meaning there?s bound to be a hotel that?s right for you.

That?s especially good news considering that finding a good deal may get a little tougher for travelers in 2012. Business data firm TravelClick predicts that, after a long slump in hotel prices, rates will rise almost 4 percent in 2012, thanks to increased demand as the economy recovers.

At least there?s no need to compromise on quality. The Waldorf Astoria Orlando, for instance, has outposts of celebrated dining venues from the flagship property in New York. Not to mention two pools and a spa with 21 treatment rooms. But at $159 a night, its rate is less than half that in Manhattan ? and you get a free shuttle to Disney World. Besides, visiting a city that?s not on the West Coast or in the Northeast practically guarantees that other costs, such as dining and entertainment, will be more affordable, too.

Top affordable hotels?such as the Waldorf Astoria Orlando also defy the conventional wisdom that you should look to a city?s outlying neighborhoods for a good deal. In Santa Fe, N.M.,?the pueblo-style Inn of Anasazi wins over guests with its tasteful, luxurious d?cor ? handwoven rugs, paintings by acclaimed local artists, kiva-shaped gas fireplaces, and four-poster beds ? placed in the heart of the action.

Although plenty of celebrities have been spotted checking into the fashionable Inn of Anasazi, you don?t need to star in a hit movie to be able to afford its nightly rates.

More from Travel + Leisure

?

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English FA talks to Hodgson about coach's job

Associated Press Sports

updated 2:18 p.m. ET April 29, 2012

LONDON (AP) -The English Football Association approached West Bromwich Albion manager Roy Hodgson on Sunday about filling the national coach's job, almost three months after Fabio Capello's resignation.

The FA waited until the final weeks of the season to make its move to replace Capello, despite the European Championship starting in June. Tottenham manager Harry Redknapp had been considered the favorite for the job.

The FA was granted permission on Sunday by West Brom chairman Jeremy Peace to speak with Hodgson, who has coached in seven countries and led three national teams.

"Roy is the only manager we have approached and we remain on course to make an appointment within the timescale we set-out soon after Fabio Capello's departure," FA chairman David Bernstein said in a statement. "Further conversations will now take place with Roy and my Club England colleagues before any further announcements can be made."

The FA would not have to pay compensation to hire Hodgson, whose West Brom contract was due to expire at the end of the season next month.

In a 36-year coaching career, Hodgson has had spells in England, Sweden, Denmark, Norway, Switzerland and Italy, where he was twice in charge of Inter Milan.

Hodgson has also coached Finland, the United Arab Emirates and Switzerland, which he guided to the 1994 World Cup in the United States. He has also acted as a technical adviser to UEFA, European football's governing body.

He made his mark in England with Fulham, the small west London club he joined midway through the 2007-08 season and guided to its best ever finish of seventh place the following year.

He was voted manager of the year for 2009-10 by the League Managers Association for taking the Cottagers to the Europa League final.

He was subsequently lured to Liverpool, where he endured an unsuccessful six-month stint before being fired in January 2011.

But West Brom handed Hodgson a swift chance to re-establish his reputation a month later and he repaid the club's faith in him by keeping the club in the Premier League. West Brom is 10th in the standings with two matches to go this season.

? 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Roundup: Fernando Torres got his first hat trick in more than 21/2 years on Sunday to lead Chelsea to a 6-1 English Premier League win over Queens Park Rangers.

English FA talks to Hodgson about coach's job

LONDON (AP) -The English Football Association approached West Bromwich Albion manager Roy Hodgson on Sunday about filling the national coach's job, almost three months after Fabio Capello's resignation.

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April Creative Writing Competition entry. ? attila - My Telegraph

COLLEY?S ?COTSWOLD ?CAPER.


The London underground train rumbled and swayed on it?s way towards St. James Park, and had the strap-hanging traveller been stripped completely naked he could not have felt more vulnerable.?Over the weekend, newly appointed Detective Constable Robert Fabian had put his days as a uniformed constable behind him, and in his belted Trench coat, tweed jacket, Fair-Isle pullover, and flannels, he was today about to start a new phase of his career as a detective in London?s Metropolitan Police Force C.I.D.?It was almost as if his authority had vanished along with his shiny buttoned uniform, truncheon, and distinctive custodian helmet.

He was beginning to wish that he had worn a hat, though somehow his weekend flat cap hadn?t seemed quite appropriate for today?s occasion.

But if only his late father, an ex-beat sergeant copper with over twenty years service, could see him now on his way to New Scotland Yard.

Bob choked at the thought.

:

?Detective Constable Robert Fabian reporting to Detective Chief Inspector ?Koller?, he announced to the uniformed Desk Sergeant, upon his arrival in the tiled entrance hall.

The sergeant looked up over his glasses, sniffed as he stroked his moustache with finger and thumb, and snapped ?Second floor, room 212b?.

Bob started for the stairs but before he could move the sergeant halted him.

?Identification sonny!?

Bob fumbled in his pocket and handed his warrant card to the sergeant who recorded the details in a large ledger, and handed it back.

There was a glint in the sergeants eye and the flicker of a smile crossed his face, but he spoke in a flat monotone.

?Up the stairs, turn left, second door on left, knock and wait, he?ll keep you waiting, always does, best o? luck, you?ll need it!?

:

Bob?s double knock on the door brought no response and after waiting a minute or two he perched himself on a chair across the corridor. Minutes later the door opened and a burly man in his late fifties strode out and disappeared up the corridor.

Ten minutes later he was back, and with his hand on the door knob, he turned to Bob and said irascibly ?Who the bloody hell are you and what are you sitting there for ? have you nothing to do!?

Bob sprang to attention and spluttered his name and the reason for his presence.

D.C.I. Koller, for it was he, fixed Bob with piercing black eyes, twirled his waxed moustache between finger and thumb, and said gruffly, ?Well don?t just bloody well sit out there, get down to the canteen and get me a cup of tea and bring it back ?chop chop?, milk three sugars, and get one for yourself, and don?t be all morning, you?re late enough already!?

As the door closed behind the D.C.I., a chastened ?Bob said quietly to himself, ?And how do you do to you, you miserable old bugger?.

:

Ten minutes later, having found the canteen and returned to room 212b, ?Bob sat awkwardly clutching his mug of greasy tea. Koller, who was notoriously abrupt when dealing with subordinates, grimaced as he sipped his tea, before complaining ?Luke-warm, and not enough sugar?.

Bob waited as Koller selected a carved briar pipe from a rack on his desk, took a tin of ?Three Nuns? tobacco from a drawer, and rolled a measured amount of leaf lovingly in his palms. Finally, after studiously packing his pipe, he spoke briskly in the manner of a man not used to having to repeat himself.

? Right laddie, ground rules, Do?s and Don?ts!?

?You might well think yourself my second in command but in reality you are my dogsbody. You are my assistant and my shadow. Speak when you?re spoken to and not unless and until.?

?You watch, keep your ears open and listen, and above all, learn.?

?Never ever interrupt me, especially when I?m interviewing ?chummy?, that?s the suspect or felon to you, and never question my methods when we?re in company. What you hear when you?re with me remains with us except when I instruct you otherwise. Have no truck with any defence brief, ?and especially never trust any of our own legal team. Call me Sir in front of the top brass or the public, and address me as Guv?nor in private?.

Kollar reached into his desk, fished out a notebook and tossed it to Bob. ?Here! Use this, jot everything down, write it up properly every night.?

?Understood??

? Yes Sir ? Guv? gulped Bob.

?Not bloody Guv, I said Guv?nor? groaned Koller.

?Yes er, um, Guv?nor? replied Bob,

?Right, this is what?s on top of our pile now.?

Koller struck a match and didn?t speak until he?d puffed his pipe into glowing life.

?We?re leaving for Cheltenham tonight?, he said through the smoke.

?We?ve been called in by the local Force on a robbery and murder at the country house of Lord ?Peter Wimsey at Chilton Wallop. A large quantity of jewellery has gone missing from the safe and in the process somebody skewered the butler, one Douglas L. Sayers?.

?That?s all you need for now, find yourself a desk out in the office, sign out at lunchtime, go home pack a bag and meet me at two-thirty sharp at Paddington Station, platform one. Pack for two days?

?Yes Guv?nor?, Bob turned to go.

?And son!?

He turned back to Koller.

? Get yourself a hat, preferably a trilby, and grow a moustache. We might have to put up with women PC?s now but there?s no bloody need for you to look like one! And close the door behind you.?

Bob slumped onto the chair in the corridor, found the stub of a pencil in his pocket, licked it, and wrote on the first page of his new notebook ? ?Get trilby/grow tash/pack/cancel Wendsy night with Rita/ bugger!?

:

As the Cheltenham Spa Express steamed out of Paddington dead on time, Koller and Fabian found an empty First class compartment and settled in for the two hour journey. Slinging his Gladstone bag up onto the rack, Koller sunk into the corner seat after first pulling down the blinds on the corridor side of the compartment. Taking out a pouch he set about charging his pipe.

Fabian nervously eyed the ?No Smoking? signs.

Koller, displaying his psychic powers, waved his pipe and said gruffly, ?Sod ?em, if anyone tries to get in through that door, stick your warrant card under their nose and tell ?em Police Business?.

He handed Bob a thick brown envelope, boldly addressed to the Cheltenham police, ?Hang on to that and don?t pass it on until I tell you, and if anyone ever asks, I?ve never seen it. ?You were given it by someone behind the desk at the Yard.?

?Now then, put it away and pay attention!?

For the next sixty minutes, through clouds of dense Three Nuns smoke, Koller filled in all the details to hand of the happenings at Chilton Manor.

Basically the robbery had taken place during a week-long house party hosted by Lord Peter, and over thirty thousand pounds worth of ?jewellery had vanished from the safe. The robbery had taken place during the night, there was no obvious sign of a forced entry, and the safe was opened by someone almost certainly using the combination. Most of the guests were known personally to Lord Peter and the only people present who he could not vouch for had been interrogated by the local police and were being detained in residence until Koller had a chance to interview them.

The staff were a separate issue and except for a scullery maid, a Miss Christie who had vanished the night before the robbery, they were all still at the Manor. It was thought that Sayers, the murder victim, had disturbed the burglar or burglars, and had paid with his life.

They discussed the details of the case at length. Finally, Koller handed the file and a sheet of paper to Bob.

?Here?s a provisional list of suspects that the local boys drew up, based solely upon the fact that they were strangers to Lord Peter. Of course that means nothing, crooks come in all shapes and sizes and from all walks of life, it just gives us somewhere to start?.

Bob ran his finger down the list ?

:

Colonel Colman. Guest.

Miss O?Hara, the Colonel?s secretary.

Reverend Mr. Green. Guest.

Professor Cherry. Guest.

Doctor Black. Local village doctor. Guest.

Mrs. Slocombe. Guest.

Mrs. White. Agency cook brought in for week.

Miss A.Christie. Missing scullery maid.

:

?Well!? said Koller, puffing vigorously at his briar, ?what d?you think??

?I think, I think ?. I think I need a pee? stammered Bob, rising to his feet.

And before Koller could reply he opened the door and staggered out into the comparatively fresh air of the corridor. Swaying his way to the toilet he heard Koller slide the door across behind him.

?Bloody hell? Bob muttered to himself, ?his lungs must be kippered!?

He would be in no hurry to get back.

:

Leaving the toilet, where he had taken the opportunity to update his notebook (get Gladstone bag/ always travel 1st. Class/ stick to fags), Bob lowered a corridor window, stuck his head out and gulped in the fresh evening air. The keen air stung his nostrils and his head spun as he breathed deeply to cleanse the smoke from his lungs. He also collected what felt like an ounce of smutty grit beneath his eyelids as the steam from the engine raced past the window. He pulled on the strap to raise the window and returned reluctantly to the compartment to find Koller writing copious notes against the list of ?suspects?.

Koller looked up as Bob reluctantly closed the door behind him, sealing in the fug.

?What?s wrong with your eyes laddie ?? he said with a sarcastic grin. ? too much fresh air can be bad for you know, especially when it?s full of fire-ash?.

Koller put down the list, rummaged in his pocket, drew out a silver hip flask and passed it to Bob.

?Here, get some of that down you, the case can wait now until tomorrow?. Koller loosened his tie, undid his waistcoat, and knocked out his now empty pipe on the heel of his shoe before slumping back into his seat.

Koller?s face softened as he studied Bob across the compartment ?

?Sit back and relax, and allow me to tell you how you got to be here, laddie? he said.

Bob looked quizzically at his new boss who had suddenly taken on a new persona. Gone was the gruff uncompromising policeman, he was about to see a side of the Inspector that few within the Force knew existed.

Koller?s voice mellowed ?

?Your father Jack was the best all-round copper it was ever my good fortune to come across. Most of what I know, he taught me. And now, with my retirement coming up in six months time, I can do the same for you. I asked for you especially and you?re not to let him, or me, down! Savvy??

?Your father lingering ?in the uniformed branch was a waste of talent, he knew all there was to know about proper policing. But as you must know, his life was his family.?

?You, your sister Rosie, and your lovely mother Dora.?

?Not for him the irregular hours of detective work, he wanted to spend time with the family, not the Force.?

?Not that he couldn?t have coped mind you, the top brass begged him at times to go over to C.I.D., but it wasn?t what he wanted.?

Koller was in reflective mood and he took another swig from the flask.

?We were together at Sydney Street you know.? he said.

?Your Dad looked after Home Secretary Churchill that day like an uncle. ?Impetuous bugger that Churchill, if it wasn?t for your old man he would have probably ended up taking one that day, he was so bloody reckless.?

?And now he?s Chancellor ? bloody priceless!?

Koller reached for his pipe but mercifully it was only in order to suck on it reflectively, as a baby would a dummy.

?Your father helped me in one way or another on almost all of the cases that I ever solved, and now I?m going to return the favour by teaching you all that I?ve learned?.

Bob was lost for words at this entirely unexpected turn of events, but ?Kollar, lying back with his eyes half closed, continued as if Bob had ceased to exist.

?My old mentor D. I. Jupp also thought the world of Jack. Many a time he?d cry on your old man?s shoulder when that bloody Belgian amateur Poirot was poking around on his case. Him and his bloody grey cells.? ?Amateur sleuths! ?I?ve known more than a few, never give ?em the time of day laddie?.

?Sexton Blake and Tinker, a rum pair if ever there was. And Bulldog Drummond, he was another.?

?Bulldog?? Koller sniffed loudly, ?He looked like one, I?ll grant him that, but he was about as tenacious as a toy poodle.?

?And as for the Saint, that Simon Templar! He was more like Mother bloody Superior ? wore a corset you know, and some said bloomers as well!?

?Steer well clear of the lot of ?em laddie.?

The last few comments had been delivered ever more slowly and quietly, and Koller?s breathing became deeper and deeper until it developed into a snore as sleep took over.

:

Bob sought fresh air in the corridor and spent the rest of the journey reflecting upon this unexpected turn of events and what it meant for his career. The hypnotic effect of the speeding lights, allied to his thoughts as they swayed and rattled through the darkness turned the remainder of the journey into an almost surreal experience. It was to be after breakfast the following morning before Bob?s life returned to anything like normality.

:

Koller and Bob stayed overnight at ?The Red Cow? in Chilton and an early meeting was arranged next morning in the snug. Also present was Detective Sergeant William Walker, lead detective from the local force.

Entering the room Koller immediately took Walker by the hand in a firm grip. ?How?s the wife and kid?s, Willy??

?Champion Colley, couldn?t be better, and your?s??

Koller frowned and replied, ?So-So?, adding, ?This is young Bob Fabian that I told you about, old Jack?s lad?

Walker smiled benignly at Bob, ?One of the best, your old man, sorry he?s gone lad!?

Bob smiled briefly whilst all the time thinking ?What the bloody hell is going on?.

Koller gestured for them all to sit down and did the talking.

?Look laddie, this is your first lesson in how it works?, he winked at the local man.

?We?ve been called in to help the locals. They usually know their job and will have already done all the leg-work, especially when, like Willy here, they?re ex-Met.?

?We have to look good to justify our couple of days in the country so I?m about to report the name of ?chummy? to the Yard and they?ll be happy that the collar looks down to us. ?

?Willy tells his boss, on my say so, that we?ve cracked it.?

?It?s all down to trust between Willy and me.?

Bob frowned as he spoke, ?But how do we know who done it??

?That?s easy? said Koller, ?it?s the noble Lord Peter?.

?But how do you know?. Bob was lost.

?Well?, said Koller, ?first it?s obviously an inside job. And a check with the insurance boys showed up that Peter the Lord had taken out fifty thousand pounds worth of insurance only last week, and he?s got previous?.

?There?s your motive, I knew that before we left London?.

?But the suspects??, said Bob.

?Actors brought in for the charades that the house party played in the evenings, all cleared?, said Walker confidently, ?Wimsey had them there to muddy the waters?.

?And the murder??

?Sayers must have seen Lord Peter at the safe, so he done for him?, said Koller.

?What about Christie, the missing maid?? queried Bob.

?Found in Harrogate, stupid girl, some sort of personal breakdown?.

Bob dug in his toes.

?But it?s all guesswork, circumstantial ? don?t you agree, Sergeant Walker??

Walker smiled.

? I trust your Guv?nor. ?If ?he say?s it?s so, then it is. I?ll inform my Chief Constable this afternoon and let him make the arrest, he?ll be well chuffed.?

?Then I write a glowing report to the Yard saying what a help you have both been, every ones a winner!?

?Excellent?, beamed Koller, ?we?ll have a right-royal blow-out tonight, on the Yard!?

And so they did.

:

The next day Koller and Bob took the train back to London.

Koller, who was badly hung over from the previous night?s celebrations, slept until the train was approaching Swindon. As the train was rumbling into the station he roused himself and spoke to Bob for the first time that day.

?Have you still got that envelope that I gave you? The one that I know nothing about?.

Bob nodded.

?Then post it at Swindon, there?s a box on the platform?, said Koller.

Bob hesitated, but then blurted out ? ?Guv?nor, I have to say this, have we not made a terrible mistake??

Koller smiled and replied smugly, ?Not at all, that envelope contains the forensic report from the Yard Lab. concerning the specimens and samples that Willy sent up to us?.

?Only Wimsey?s fingerprints were found on the safe, and his fresh dabs were all over the sword he took from the wall and used on Sayers. ?He?s bang to right?s and he?ll cough?.

?So you knew all along?, said Bob.

Koller reached for his pipe.

?Too right I did, but that?s both our secret, and your first lesson.?

?Always keep your cards close to your chest and the joker up your sleeve!?

Bob decided that he needed a pee.

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